Matthew McConaughey kawm tiav hauv tsev kawm theem siab hauv Texas txog 30 xyoo dhau los. Nws twb muaj 49 xyoos lawm, thiab nws tseem tsis tau nqa nws daim ntawv pov thawj. Lwm hnub, tus neeg ua yeeb yam tau txiav txim siab kho qhov xwm txheej thiab thaum kawg tau txais nws daim ntawv pov thawj nrog rau lwm tus kawm tiav hauv tsev kawm. McConaughey pib nws txoj haujlwm ua yeeb yam xyoo 1991 thaum nws nyob hauv tsev kawm qib siab. Nws thawj cov haujlwm tau tua hauv kev tshaj tawm. Xyoo 1992 Matthew McConaughey tau koom nrog hauv kev ua yeeb yaj kiab ntawm zaj yeeb yaj kiab "Unsolved Mysteries". McConaughey tau ua nws thawj lub luag haujlwm tseem ceeb hauv Joel Schumacher zaj yeeb yaj kiab "Sijhawm Tua", tab sis kev nyiam ua yeeb yaj kiab lom zem "Tus Npaj Kev Sib Yuav" thiab "Yuav Ua Li Cas Poob Ib Tug Txiv Neej Hauv 10 Hnub" coj nws mus rau qhov muaj koob npe tiag.
Tsis tas li hauv Hollywood, tus neeg ua yeeb yam tau hwm ntau dua ua tsaug rau Dallas Buyers Club thiab TV series True Detective. Xyoo 2013, McConaughey yeej qhov khoom plig Academy rau nws lub luag haujlwm hauv Dallas Buyers Club. Txog lub luag haujlwm ntawm tus kws kho mob cov neeg mob hluav taws xob McConaughey poob 22 kg.
McConaughey tau koom tes nrog nws tus poj niam, Camila Alves, los tsim thiab txhawb nqa Just Keep Livin Foundation, tsis yog koom haum koom siab koom siab uas txhawb txoj kev noj qab haus huv ntawm cov tub ntxhais kawm theem siab.
